Mechanisms of protein–material binding
Proteins often lose stability and function in complex biological environments due to poorly understood interfacial interactions. We investigate the mechanisms governing protein–material interfaces to uncover how these interactions control protein behaviour, building the mechanistic foundation needed to design systems that perform reliably in real biological settings.
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Computational design frameworks
Engineering protein systems is limited by our ability to predict how they behave in complex environments. We develop computational tools and predictive frameworks that connect molecular features to interfacial behaviour, enabling rational, design-led engineering of biomolecular interfaces rather than trial and error.
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Nanostructured delivery platforms
Effective protein therapeutics require precise control over stability, transport, and function. We design nanostructured and supramolecular platforms that protect their cargo and enable controlled delivery, translating our mechanistic and predictive insights into next-generation therapeutic systems with improved performance.
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